Automated Hematology

Hematology automation has progressed steadily since Wallace Coulter first applied electrical impedance technology to counting red cells and white cells. By the 1980s, most hematology laboratories were reporting out a 7-parameter complete blood count (CBC) and three-part differential obtained from a single aspiration on a stand-alone, bench-top instrument. Eventually, this process was upgraded even further when it became possible to obtain these results without uncapping the sample. When this became state-of-the-art, CBC turnaround time (TAT) was primarily dependent on how fast a laboratorian could do a manual 100-cell differential and/or a manual reticulocyte count.