Immunohematology are commonly known as blood banking is a branch of hematology which studies antigen-antibody reactions and analogous phenomena as they relate to the pathogenesis and clinical manifestations of blood disorders. This is the laboratory medicine dealing with preparing blood components, blood for appropriate selection and transfusion and components that are compatible for transfusion which is helpful for the case of severe blood loss or low blood levels. Red blood cells contain antigens and protein markers on their surfaces, if recipient or donors red blood cells doesn’t contain this antigen the antigen lacking individual will lead to form antibodies which destroys the red blood cells